Anti-ACAT1 Polyclonal Antibody
Cat: K108282P
Summary:
| 【Product name】：Anti-ACAT1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：38 | 【Swiss Prot】：P24752 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of Human ACAT1 | |
| 【Public Immunogen Range】：375-425/427aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway; an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA; catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA. Thereby; it plays a major role in ketone body metabolism.
Verified picture:
Immunohistochemistry of paraffin-embedded Human colorectal cancer with ACAT1 antibody diluted at 1:100.
Western blot analysis with ACAT1 antibody diluted at 1:2000;Lane: Rat brain.