Anti-ACMSD Polyclonal Antibody
Cat: K108315P
Summary:
| 【Product name】：Anti-ACMSD Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：130013 | 【Swiss Prot】：Q8TDX5 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:2000-5000. | |
| 【Immunogen】：Recombinant protein of human ACMSD | |
| 【Public Immunogen Range】：1-336aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS
Verified picture:
Western blot analysis with ACMSD antibody diluted at 1:4000;Lane: Rat kidney.