Anti-HMGB2 Polyclonal Antibody
Cat: K108316P
Summary:
| 【Product name】：Anti-HMGB2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3148 | 【Swiss Prot】：P26583 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:2000-5000. IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human HMGB2 | |
| 【Public Immunogen Range】：1-209aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.
Verified picture:
Immunohistochemistry of paraffin-embedded Human colorectal cancer with HMGB2 antibody diluted at 1:80.
Western blot analysis with HMGB2 antibody diluted at 1:4000;Lane: HL-60,Jurkat,U937,THP-1,Raw264.7,NIH3T3.