Anti-MTHFS Polyclonal Antibody
Cat: K108343P
Summary:
| 【Product name】：Anti-MTHFS Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：10588 | 【Swiss Prot】：P49914 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human MTHFS | |
| 【Public Immunogen Range】：1-203aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, a precursor of reduced folates involved in 1-carbon metabolism. An increased activity of the encoded protein can result in an increased folate turnover rate and folate depletion. Three transcript variants encoding two different isoforms have been found for this gene.
Verified picture:
Immunohistochemistry of paraffin-embedded Human colorectal cancer with MTHFS antibody diluted at 1:100.
Western blot analysis with MTHFS antibody diluted at 1:2000;Lane: Jurkat,K562,MCF7,U937,HeLa,Mouse liver.