Anti-RNASEH2B Polyclonal Antibody
Cat: K108363P
Summary:
| 【Product name】：Anti-RNASEH2B Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：79621 | 【Swiss Prot】：Q5TBB1 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:100-300. | |
| 【Immunogen】：Recombinant protein of human RNASEH2B | |
| 【Public Immunogen Range】：1-312aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. The protein encoded by this gene is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Aicardi-Goutieres syndrome type 2 (AGS2).
Verified picture:
Immunohistochemistry of paraffin-embedded Human stomach cancer with RNASEH2B antibody diluted at 1:200.
Western blot analysis with RNASEH2B antibody diluted at 1:2000;Lane: Raji,HeLa,MCF7,THP-1,HL-60.