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Anti-RNASEH2B Polyclonal Antibody - FITC
Cat: K108363P - FITC
Summary:
【Product name】:Anti-RNASEH2B Polyclonal Antibody - FITC 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:79621 【Swiss Prot】:Q5TBB1
【Tested applications】:ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human RNASEH2B
【Public Immunogen Range】:1-312aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. The protein encoded by this gene is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Aicardi-Goutieres syndrome type 2 (AGS2).
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