Anti-DDI1 Polyclonal Antibody - Biotin
Cat: K108381P - Biotin
Summary:
| 【Product name】：Anti-DDI1 Polyclonal Antibody - Biotin | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：414301 | 【Swiss Prot】：Q8WTU0 |
| 【Tested applications】：WB ELISA IHC ICC | |
| 【Recommended dilution】：WB 1:50-200. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human DDI1 | |
| 【Public Immunogen Range】：1-396aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Probable aspartic protease. Seems to act as a proteasomal shuttle which links the proteasome and replication fork proteins like RTF2 . Required, with DDI2, for cellular survival following replication stress. Together or redudantly with DDI2, removes RTF2 from stalled forks to allow cell cycle progression after replication stress and maintains genome integrity.
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