Anti-BMPR1A Polyclonal Antibody
Cat: K108390P
Summary:
| 【Product name】：Anti-BMPR1A Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：657 | 【Swiss Prot】：P36894 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:2000-5000. IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human BMPR1A | |
| 【Public Immunogen Range】：20-70/532aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6.
Verified picture:
Immunohistochemistry of paraffin-embedded Human colorectal cancer with BMPR1A antibody diluted at 1:100.
Western blot analysis with BMPR1A antibody diluted at 1:4000;Lane: Jurkat.