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Anti-BMPR1A Polyclonal Antibody - SAlexa Fluor 647
Cat: K108390P - SAlexa Fluor 647
Summary:
【Product name】:Anti-BMPR1A Polyclonal Antibody - SAlexa Fluor 647 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:657 【Swiss Prot】:P36894
【Tested applications】:FC ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:A synthetic peptide of human BMPR1A
【Public Immunogen Range】:20-70/532aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6.
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