Anti-POLB Polyclonal Antibody - SAlexa Fluor 647
Cat: K108411P - SAlexa Fluor 647
Summary:
| 【Product name】：Anti-POLB Polyclonal Antibody - SAlexa Fluor 647 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：5423 | 【Swiss Prot】：P06746 |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human POLB | |
| 【Public Immunogen Range】：285-335/335aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.
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