Anti-CYSLTR1 Polyclonal Antibody - SAlexa Fluor 532
Cat: K108423P - SAlexa Fluor 532
Summary:
| 【Product name】：Anti-CYSLTR1 Polyclonal Antibody - SAlexa Fluor 532 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：10800 | 【Swiss Prot】：Q9Y271 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:1000-3000. | |
| 【Immunogen】：A synthetic peptide of human CYSLTR1 | |
| 【Public Immunogen Range】：285-335/337aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4.
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