Anti-NFATC2IP Polyclonal Antibody - SAlexa Fluor 594
Cat: K108447P - SAlexa Fluor 594
Summary:
| 【Product name】：Anti-NFATC2IP Polyclonal Antibody - SAlexa Fluor 594 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：84901 | 【Swiss Prot】：Q8NCF5 |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human NFATC2IP | |
| 【Public Immunogen Range】：369-419/419aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
In T-helper 2 (Th2) cells, regulates the magnitude of NFAT-driven transcription of a specific subset of cytokine genes, including IL3, IL4, IL5 and IL13, but not IL2. Recruits PRMT1 to the IL4 promoter; this leads to enhancement of histone H4 'Arg-3'-methylation and facilitates subsequent histone acetylation at the IL4 locus, thus promotes robust cytokine expression. Down-regulates formation of poly-SUMO chains by UBE2I/UBC9.
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