Anti-Artemis (phospho Ser516) Polyclonal Antibody - FITC
Cat: K009394P - FITC
Summary:
| 【Product name】：Anti-Artemis (phospho Ser516) Polyclonal Antibody - FITC | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：64421 | 【Swiss Prot】：Q96SD1 |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human Artemis (phospho Ser516) | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This protein exhibits single-strand specific 5'-3' exonuclease activity in isolation and acquires endonucleolytic activity on 5' and 3' hairpins and overhangs when in a complex with PRKDC. The latter activity is required specifically for the resolution of closed hairpins prior to the formation of the coding joint. May also be required for the repair of complex DSBs induced by ionizing radiation, which require substantial end-processing prior to religation by non homologous end joining.
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