Anti-HSD3B7 Polyclonal Antibody
Cat: K108543P
Summary:
| 【Product name】：Anti-HSD3B7 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：80270 | 【Swiss Prot】：Q9H2F3 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:100-300. | |
| 【Immunogen】：A synthetic peptide of Human HSD3B7 | |
| 【Public Immunogen Range】：230-280/369aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. HSD VII is active against four 7-alpha-hydroxylated sterols. Does not metabolize several different C(19/21) steroids as substrates. Involved in bile acid synthesis. Plays a key role in cell positioning and movement in lymphoid tissues by mediating degradation of 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC): 7-alpha,25-OHC acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells.
Verified picture:
Immunohistochemistry of paraffin-embedded Human liver cancer with HSD3B7 antibody diluted at 1:200.