Anti-PKMYT1 Polyclonal Antibody - SAlexa Fluor 594
Cat: K108708P - SAlexa Fluor 594
Summary:
| 【Product name】：Anti-PKMYT1 Polyclonal Antibody - SAlexa Fluor 594 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：9088 | 【Swiss Prot】：Q99640 |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of Human PKMYT1 | |
| 【Public Immunogen Range】：295-345/499aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase specifically when CDK1 is complexed to cyclins. Mediates phosphorylation of CDK1 predominantly on 'Thr-14'. Also involved in Golgi fragmentation. May be involved in phosphorylation of CDK1 on 'Tyr-15' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect. May be a downstream target of Notch signaling pathway during eye development.
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