Anti-MDM4 Polyclonal Antibody - Biotin
Cat: K108710P - Biotin
Summary:
| 【Product name】：Anti-MDM4 Polyclonal Antibody - Biotin | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：4194 | 【Swiss Prot】：O15151 |
| 【Tested applications】：WB ELISA IHC ICC | |
| 【Recommended dilution】：WB 1:50-200. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of Human MDM4 | |
| 【Public Immunogen Range】：405-455/490aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions.
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