Anti-SIGLEC8 Polyclonal Antibody
Cat: K108723P
Summary:
| 【Product name】：Anti-SIGLEC8 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：27181 | 【Swiss Prot】：Q9NYZ4 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of Human SIGLEC8 | |
| 【Public Immunogen Range】：45-95/499aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Putative adhesion molecule that mediates sialic-acid dependent binding to red blood cells. Preferentially binds to alpha-2,3-linked sialic acid. Also binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. Recognizes simultaneously epitopes having a terminal N-acetylneuraminic acid (sialic acid) and an underlying 6-O-sulfated galactose. Preferentially binds to Gal-6-sulfated sialyl-Lewis X glycan epitopes.
Verified picture:
Immunohistochemistry of paraffin-embedded Human stomach cancer with SIGLEC8 antibody diluted at 1:100.
Western blot analysis with SIGLEC8 antibody diluted at 1:2000;Lane: A431,HMC1,THP-1,293T,Mouse liver.