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Anti-SIGLEC8 Polyclonal Antibody - Cy7
Cat: K108723P - Cy7
Summary:
【Product name】:Anti-SIGLEC8 Polyclonal Antibody - Cy7 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:27181 【Swiss Prot】:Q9NYZ4
【Tested applications】:WB,IHC
【Recommended dilution】:WB 1:1000-3000. IHC 1:50-200.
【Immunogen】:A synthetic peptide of Human SIGLEC8
【Public Immunogen Range】:45-95/499aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Putative adhesion molecule that mediates sialic-acid dependent binding to red blood cells. Preferentially binds to alpha-2,3-linked sialic acid. Also binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. Recognizes simultaneously epitopes having a terminal N-acetylneuraminic acid (sialic acid) and an underlying 6-O-sulfated galactose. Preferentially binds to Gal-6-sulfated sialyl-Lewis X glycan epitopes.
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