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Anti-BACE1 Polyclonal Antibody - SAlexa Fluor 405
Cat: K108725P - SAlexa Fluor 405
Summary:
【Product name】:Anti-BACE1 Polyclonal Antibody - SAlexa Fluor 405 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:23621 【Swiss Prot】:P56817
【Tested applications】:WB
【Recommended dilution】:WB 1:1000-3000.
【Immunogen】:A synthetic peptide of Human BACE1
【Public Immunogen Range】:15-65/501aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. Cleaves CHL1.
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