Anti-DIABLO Polyclonal Antibody
Cat: K000368P
Summary:
| 【Product name】：Anti-DIABLO Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：56616 | 【Swiss Prot】：Q9NR28 |
| 【Tested applications】：IHC,WB,IP | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:50-200. IP 0.5μg-4μg. | |
| 【Immunogen】：Recombinant protein of human DIABLO | |
| 【Public Immunogen Range】：56-239aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms.
Verified picture:
Western blot analysis with DIABLO antibody diluted at 1:1000;Lane:SW620,BT-474,Mouse spleen
Immunohistochemistry of paraffin-embedded Rat testis with DIABLO antibody diluted at 1:100