Anti-MyD88 Polyclonal Antibody
Cat: K001785P
Summary:
| 【Product name】：Anti-MyD88 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：4615 | 【Swiss Prot】：Q99836 |
| 【Tested applications】：IF,WB | |
| 【Recommended dilution】：WB 1:100-500. IF 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human MyD88 | |
| 【Public Immunogen Range】：20-140aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.
Verified picture:
Western blot analysis with MyD88 antibody diluted at 1:1000;Lane: A549 Mouse lung Mouse uterus Rat lung.
Immunofluorescence analysis of Raw264.7 cells using MyD88 antibody diluted at 1:100.
Immunofluorescence analysis of U2OS cells using MyD88 antibody diluted at 1:100.