Anti-GPER1 Polyclonal Antibody
Cat: K001889P
Summary:
| 【Product name】：Anti-GPER1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：2852 | 【Swiss Prot】：Q99527 |
| 【Tested applications】：WB,IF | |
| 【Recommended dilution】：WB 1:500-1000. IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of human GPER1 | |
| 【Public Immunogen Range】：307-375aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized.
Verified picture:
Immunohistochemistry of paraffin-embedded Human liver cancer with GPER1 antibody diluted at 1:100
Western blot analysis with GPER1 antibody diluted at 1:1000;Lane: Mouse heart.
Immunofluorescence analysis of NIH3T3 cells using GPER1 antibody diluted at 1:100.