Anti-MTHFD2 Polyclonal Antibody
Cat: K001972P
Summary:
| 【Product name】：Anti-MTHFD2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：10797 | 【Swiss Prot】：P13995 |
| 【Tested applications】：IF,IHC,WB | |
| 【Recommended dilution】：WB 1:500-1000. IHC 1:50-200. IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of human MTHFD2 | |
| 【Public Immunogen Range】：40-250aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7.
Verified picture:
Western blot analysis with MTHFD2 antibody diluted at 1:1000;Lane: 293T LO2 Jurkat HeLa Mouse spleen Mouse testis.
Immunohistochemistry of paraffin-embedded Human pancreatic cancer with MTHFD2 antibody diluted at 1:100
Immunofluorescence analysis of NIH3T3 using MTHFD2 antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded human mammary cancer with MTHFD2 antibody diluted at 1:100.
Immunofluorescence analysis of C6 cells using MTHFD2 antibody diluted at 1:100.