Anti-COL2A1 Polyclonal Antibody - SAlexa Fluor 532
Cat: K002832P - SAlexa Fluor 532
Summary:
| 【Product name】：Anti-COL2A1 Polyclonal Antibody - SAlexa Fluor 532 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1280 | 【Swiss Prot】：P02458 |
| 【Tested applications】：WB,IF | |
| 【Recommended dilution】：WB 1:500-1000. IF 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human COL2A1 | |
| 【Public Immunogen Range】：1220-1282aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene.
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