Anti-KNG1 Polyclonal Antibody
Cat: K002914P
Summary:
| 【Product name】：Anti-KNG1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3827 | 【Swiss Prot】：P01042 |
| 【Tested applications】：IF,WB | |
| 【Recommended dilution】：WB 1:100-500. IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of human KNG1 | |
| 【Public Immunogen Range】：148-427aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.
Verified picture:
Western blot analysis with KNG1 antibody diluted at 1:1000;Lane: Rat lung.
Immunofluorescence analysis of L929 cells using KNG1 antibody diluted at 1:100.