Anti-KNG1 Polyclonal Antibody - SAlexa Fluor 640
Cat: K002914P - SAlexa Fluor 640
Summary:
| 【Product name】：Anti-KNG1 Polyclonal Antibody - SAlexa Fluor 640 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3827 | 【Swiss Prot】：P01042 |
| 【Tested applications】：IF,WB | |
| 【Recommended dilution】：WB 1:100-500. IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of human KNG1 | |
| 【Public Immunogen Range】：148-427aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.
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