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Anti-NUMBL Polyclonal Antibody
Cat: K003250P
Summary:
【Product name】:Anti-NUMBL Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:9253 【Swiss Prot】:Q9Y6R0
【Tested applications】:WB
【Recommended dilution】:WB 1:500-2000.
【Immunogen】:Recombinant protein of human NUMBL
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Numb-like (Numbl or Nbl) binds Notch and is an intracellular modulator of Notch signaling pathway. Numbl contains a phosphotyrosine binding (PTB) domain that could bind the Y682 motif present in the cytoplasmic tail of APP. Deduced molecular weight of Numbl is 72 kDa.
Verified picture:
Western blot analysis with NUMBL antibody diluted at 1:1000;Lane:Mouse kidney