Anti-DNM1L Polyclonal Antibody
Cat: K003440P
Summary:
| 【Product name】：Anti-DNM1L Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：10059 | 【Swiss Prot】：O00429 |
| 【Tested applications】：WB,IF,IHC | |
| 【Recommended dilution】：WB 1:500-2000.IHC 1:50-200.IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human DNM1L | |
| 【Public Immunogen Range】：411-710aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms.
Verified picture:
Western blot analysis with DNM1L antibody diluted at 1:1000;Lane: Mouse brain Rat brain.
Immunohistochemistry of paraffin-embedded rat brain with DNM1L antibody diluted at 1:100.
Immunofluorescence analysis of NIH3T3 cells using DNM1L antibody diluted at 1:100.