Anti-DNMT3A Polyclonal Antibody
Cat: K003621P
Summary:
| 【Product name】：Anti-DNMT3A Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1788 | 【Swiss Prot】：Q9Y6K1 |
| 【Tested applications】：WB,IF | |
| 【Recommended dilution】：WB 1:500-2000.IF 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human DNMT3A | |
| 【Public Immunogen Range】：500-700aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.
Verified picture:
Western blot analysis with DNMT3A antibody diluted at 1:1000;Lane: Mouse spleen,Mouse skeletal muscle
Immunohistochemistry of paraffin-embedded human kidney with DNMT3A antibody diluted at 1:100
Immunofluorescence analysis of A549 cells using DNMT3Aantibody diluted at 1:100.