Anti-COMP Polyclonal Antibody - Cy3.5
Cat: K004228P - Cy3.5
Summary:
| 【Product name】：Anti-COMP Polyclonal Antibody - Cy3.5 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1311 | 【Swiss Prot】：P49747 |
| 【Tested applications】：IF,WB | |
| 【Recommended dilution】：WB 1:500-1000. IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of human COMP | |
| 【Public Immunogen Range】：20-160aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Contraction or expansion of a 5 aa aspartate repeat and other mutations can cause pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).
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