Anti-SNCA Polyclonal Antibody
Cat: K005093P
Summary:
| 【Product name】：Anti-SNCA Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：6622 | 【Swiss Prot】：P37840 |
| 【Tested applications】：WB,IF | |
| 【Recommended dilution】：WB 1:500-1000. IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of human SNCA | |
| 【Public Immunogen Range】：59-140aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.
Verified picture:
Western blot analysis with SNCA antibody diluted at 1:1000;Lane: Mouse brain Rat brain.
Immunohistochemistry of paraffin-embedded ovarian cancer (hu) using Anti-SNCA Rabbit Polyclonal Antibody at dilution of 1:100 (100x lens).
Immunofluorescence analysis of Neuro-2a cells using SNCA antibody diluted at 1:100.