Anti-SNCA Polyclonal Antibody - SAlexa Fluor 633
Cat: K005093P - SAlexa Fluor 633
Summary:
| 【Product name】：Anti-SNCA Polyclonal Antibody - SAlexa Fluor 633 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：6622 | 【Swiss Prot】：P37840 |
| 【Tested applications】：WB,IF | |
| 【Recommended dilution】：WB 1:500-1000. IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of human SNCA | |
| 【Public Immunogen Range】：59-140aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.
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