Anti-ATP6AP2 Polyclonal Antibody - FITC
Cat: K108764P - FITC
Summary:
| 【Product name】：Anti-ATP6AP2 Polyclonal Antibody - FITC | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：10159 | 【Swiss Prot】：O75787 |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of Human ATP6AP2 | |
| 【Public Immunogen Range】：50-100/350aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Multifunctional protein which functions as a renin, prorenin cellular receptor and is involved in the assembly of the proton-transporting vacuolar (V)-ATPase protein pump. May mediate renin-dependent cellular responses by activating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, it may also play a role in the renin-angiotensin system (RAS). Probably by controlling the assembly of the V-ATPase pump and thus the acidification of the endo-lysosomal system, plays a role in many neuronal processes including synapse morphology and synaptic transmission.
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