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Anti-MSTN Polyclonal Antibody - SAlexa Fluor 405
Cat: K108778P - SAlexa Fluor 405
Summary:
【Product name】:Anti-MSTN Polyclonal Antibody - SAlexa Fluor 405 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:2660 【Swiss Prot】:O14793
【Tested applications】:IHC
【Recommended dilution】:IHC 1:100-300.
【Immunogen】:A synthetic peptide of Human MSTN
【Public Immunogen Range】:140-190/375aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals.
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