Anti-Notch 2 Polyclonal Antibody
Cat: K009552P
Summary:
| 【Product name】：Anti-Notch 2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：4853 | 【Swiss Prot】：Q04721 |
| 【Tested applications】：IF,IHC,ELISA | |
| 【Recommended dilution】：ELISA 1:5000-10000. IHC 1:100-500. IF 1:100-500. | |
| 【Immunogen】：A synthetic peptide of human Notch 2 | |
| 【Public Immunogen Range】：1501-1700/2471aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs.
Verified picture:
Immunohistochemistry of paraffin-embedded Mouse brain with Notch 2 antibody diluted at 1:200
Immunohistochemistry of paraffin-embedded Mouse brain with Notch 2 antibody diluted at 1:400.