Anti-Notch 2 Polyclonal Antibody - RBITC
Cat: K009552P - RBITC
Summary:
| 【Product name】：Anti-Notch 2 Polyclonal Antibody - RBITC | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：4853 | 【Swiss Prot】：Q04721 |
| 【Tested applications】：WB ELISA IHC ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human Notch 2 | |
| 【Public Immunogen Range】：1501-1700/2471aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs.
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