Anti-CENPA Polyclonal Antibody
Cat: K009577P
Summary:
| 【Product name】：Anti-CENPA Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1058 | 【Swiss Prot】：P49450 |
| 【Tested applications】：ELISA,IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000. ELISA 1:5000-10000. IHC 1:100-500. | |
| 【Immunogen】：A synthetic peptide of human CENPA | |
| 【Public Immunogen Range】：65-140/140aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division. The CENPA-H4 heterotetramer can bind DNA by itself (in vitro).
Verified picture:
Immunohistochemistry of paraffin-embedded rat kidney with CENPA antibody diluted at 1:200.