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Anti-BDNF Polyclonal Antibody
Cat: K009652P
Summary:
【Product name】:Anti-BDNF Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:627 【Swiss Prot】:P23560
【Tested applications】:WB,IHC,ICC,IF,ELISA,FCM
【Recommended dilution】:WB 1:500-2000. ELISA 1:5000-10000. IHC 1:100-500. FCM 1μg/Test. ICC 1:100-500. IF 1:200-800.
【Immunogen】:A synthetic peptide of human BDNF
【Public Immunogen Range】:151-247/247aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
Verified picture:
Western blot analysis with BDNF antibody diluted at 1:300;Lane: Mouse Cerebrum Mouse Cerebellum Rat Cerebrum.
Immunohistochemistry of paraffin-embedded Mouse brain with BDNF antibody diluted at 1:300
Immunohistochemistry of paraffin-embedded Mouse brain with BDNF antibody diluted at 1:400.
Immunofluorescence analysis of U251 cell using BDNF antibody diluted at 1:200.