Anti-FTO Polyclonal Antibody - HRP
Cat: K009677P - HRP
Summary:
| 【Product name】：Anti-FTO Polyclonal Antibody - HRP | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：79068 | 【Swiss Prot】：Q9C0B1 |
| 【Tested applications】：WB,IHC,IF,ELISA | |
| 【Recommended dilution】：WB 1:500-2000. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human FTO | |
| 【Public Immunogen Range】：165-265/505aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation. Has highest activity towards single-stranded RNA containing 3-methyluracil, followed by single-stranded DNA containing 3-methylthymine. Has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine. Has no activity towards 1-methylguanine. Has no detectable activity towards double-stranded DNA. Requires molecular oxygen, alpha-ketoglutarate and iron. Contributes to the regulation of the global metabolic rate, energy expenditure and energy homeostasis. Contributes to the regulation of body size and body fat accumulation.
Verified picture: