Anti-CDKN1B/p27 KIP1 Polyclonal Antibody
Cat: K009714P
Summary:
| 【Product name】：Anti-CDKN1B/p27 KIP1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1027 | 【Swiss Prot】：P46527 |
| 【Tested applications】：ELISA,FCM,IF,IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000. ELISA 1:5000-10000. IP 1:20-100. IHC 1:100-500. FCM 1μg/Test . IF 1:200-800. | |
| 【Immunogen】：A synthetic peptide of human CDKN1B/p27 KIP1 | |
| 【Public Immunogen Range】：101-198/198aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry.
Verified picture:
Western blot analysis with CDKN1B/p27 KIP 1 antibody diluted at 1:1000;Lane: 293T.
Immunofluorescence analysis of MCF7 cell using CDKN1B antibody diluted at 1:200.