Anti-Bax Polyclonal Antibody
Cat: K009716P
Summary:
| 【Product name】：Anti-Bax Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：581 | 【Swiss Prot】：Q07812 |
| 【Tested applications】：WB,ICC,IHC,ELISA,FCM,IF | |
| 【Recommended dilution】：WB 1:500-2000. ELISA 1:5000-10000. IHC 1:100-500. FCM 1μg /test. ICC 1:100. IF 1:100-500. | |
| 【Immunogen】：A synthetic peptide of human Bax | |
| 【Public Immunogen Range】：84-175/192aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Verified picture:
Western blot analysis with Bax antibody diluted at 1:1000;Lane: Mouse Testis Rat Kidney Rat Testis.
Immunohistochemistry of paraffin-embedded Rat lung with Bax antibody diluted at 1:200
Immunofluorescence analysis of SH-SY5Y cells using Bax antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunohistochemistry of paraffin-embedded human brain glioma with Bax antibody diluted at 1:400.
Immunofluorescence analysis of Sh-sy5y cell using Bax antibody diluted at 1:100.