Anti-Bax Polyclonal Antibody - Biotin
Cat: K009716P - Biotin
Summary:
| 【Product name】：Anti-Bax Polyclonal Antibody - Biotin | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：581 | 【Swiss Prot】：Q07812 |
| 【Tested applications】：WB ELISA IHC ICC | |
| 【Recommended dilution】：WB 1:50-200. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human Bax | |
| 【Public Immunogen Range】：84-175/192aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
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