Anti-CASP1 Polyclonal Antibody
Cat: K009718P
Summary:
| 【Product name】：Anti-CASP1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：834 | 【Swiss Prot】：P29466 |
| 【Tested applications】：FCM,IF,IHC,WB,ELISA | |
| 【Recommended dilution】：WB 1:500-2000. ELISA 1:5000-10000. IHC 1:100-500. FCM 1ug/Test. IF 1:100-500. | |
| 【Immunogen】：A synthetic peptide of human CASP1 | |
| 【Public Immunogen Range】：320-404/404aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.
Verified picture:
Immunohistochemistry of paraffin-embedded Rat brain with CASP1 antibody diluted at 1:300
Immunohistochemistry of paraffin-embedded Mouse brain with Caspase-1 P10 antibody diluted at 1:500.