Anti-BID Polyclonal Antibody
Cat: K108817P
Summary:
| 【Product name】：Anti-BID Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：637 | 【Swiss Prot】：P55957 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human BID | |
| 【Public Immunogen Range】：1-195aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.
Verified picture:
Immunohistochemistry of paraffin-embedded Human colorectal cancer with BID antibody diluted at 1:100
Western blot analysis with BID antibody diluted at 1:2000;Lane: Jurkat,A431,293T,HL-60,THP-1