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Anti-BID Polyclonal Antibody - HRP
Cat: K108817P - HRP
Summary:
【Product name】:Anti-BID Polyclonal Antibody - HRP 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Octanoic acid-ammonium sulfate precipitation
【Gene ID】:637 【Swiss Prot】:P55957
【Tested applications】:WB,IHC
【Recommended dilution】:WB 1:500-2000. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200
【Immunogen】:Recombinant protein of human BID
【Public Immunogen Range】:1-195aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.
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