Anti-PUF60 Polyclonal Antibody
Cat: K108847P
Summary:
| 【Product name】：Anti-PUF60 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：22827 | 【Swiss Prot】：Q9UHX1 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human PUF60 | |
| 【Public Immunogen Range】：197-542aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. The encoded protein forms a complex with the far upstream DNA element (FUSE) and FUSE-binding protein at the myelocytomatosis oncogene (MYC) promoter. This complex represses MYC transcription through the core-TFIIH basal transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Verified picture:
Immunohistochemistry of paraffin-embedded Human cervical cancer with PUF60 antibody diluted at 1:100
Western blot analysis with PUF60 antibody diluted at 1:2000;Lane: THP-1,Hela,MCF7,293T,A431,Mouse thymus,Rat heart,A549,Mouse testis