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Anti-FGFR1OP Polyclonal Antibody
Cat: K108881P
Summary:
【Product name】:Anti-FGFR1OP Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Octanoic acid-ammonium sulfate precipitation
【Gene ID】:11116 【Swiss Prot】:O95684
【Tested applications】:IHC
【Recommended dilution】:IHC 1:100-300.
【Immunogen】:A synthetic peptide of Human FGFR1OP
【Public Immunogen Range】:30-80/399aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified.
Verified picture:
Immunohistochemistry of paraffin-embedded Human colorectal cancer with FGFR1OP antibody diluted at 1:200