Anti-ITPKA Polyclonal Antibody
Cat: K108934P
Summary:
| 【Product name】：Anti-ITPKA Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3706 | 【Swiss Prot】：P23677 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:1000-3000. | |
| 【Immunogen】：A synthetic peptide of Human ITPKA | |
| 【Public Immunogen Range】：411-461/461aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro.
Verified picture:
Western blot analysis with ITPKA antibody diluted at 1:2000;Lane:K-562,HepG2