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Anti-FRS2 Polyclonal Antibody - SAlexa Fluor 532
Cat: K108939P - SAlexa Fluor 532
Summary:
【Product name】:Anti-FRS2 Polyclonal Antibody - SAlexa Fluor 532 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:10818 【Swiss Prot】:Q8WU20
【Tested applications】:WB,IHC
【Recommended dilution】:WB 1:1000-3000. IHC 1:50-200.
【Immunogen】:A synthetic peptide of Human FRS2
【Public Immunogen Range】:1-51/508aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.
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