Anti-TNFRSF1A Polyclonal Antibody - FITC
Cat: K108969P - FITC
Summary:
| 【Product name】：Anti-TNFRSF1A Polyclonal Antibody - FITC | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：7132 | 【Swiss Prot】：P19438 |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human TNFRSF1A | |
| 【Public Immunogen Range】：320-370/455aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.
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